InAs(ZnCdS) Quantum Dots Optimized for Biological Imaging in the Near-Infrared
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Bawendi_InAs.pdf
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Author(s) • • • • • • •
Allen, Peter M.
Liu, Wenhao
Chauhan, Vikash P.
Lee, Jungmin
Ting, Alice Y.
Fukumura, Dai
Jain, Rakesh K.
Bawendi, Moungi G.
Date Issued
December 2009
Journal
Journal of the American Chemical Society
Publisher
American Chemical Society
Citation
Allen, Peter M. et al. “InAs(ZnCdS) Quantum Dots Optimized for Biological Imaging in the Near-Infrared.” Journal of the American Chemical Society 132.2 (2010): 470–471. Web.
Version
Author's final manuscript
Abstract
We present the synthesis of InAs quantum dots (QDs) with a ZnCdS shell with bright and stable emission in the near-infrared (NIR, 700−900 nm) region for biological imaging applications. We demonstrate how NIR QDs can image tumor vasculature in vivo at significantly deeper penetration depths and with higher contrast than visible emitting CdSe(CdS) QDs. Targeted cellular labeling is also presented and may enable multiplexed and low autofluorescence cellular imaging.
MIT Department
Massachusetts Institute of Technology. Department of Chemistry
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DOI of Published Version
https://doi.org/10.1021/ja908250r