Computer-aided design for multilayer microfluidic chips
Name
503453622-MIT.pdf
Description
Full printable version
Size
12.66 MB
Format
Adobe PDF
Checksum (MD5)
722172778c84f611a31efce842f9d9f1
Author(s)
Amin, Nada
Advisor(s)
Saman P. Amarasinghe.
Date Issued
2009
Publisher
Massachusetts Institute of Technology
Abstract
Microfluidic chips fabricated by multilayer soft lithography are emerging as "lab-on-a-chip" systems that can automate biological experiments. As we are able to build more complex microfluidic chips with thousands of components, it becomes possible to build devices which can be programmatically changed to solve multiple problems. However, the current design methodology does not scale. In this thesis, we introduce design automation techniques to multilayer soft lithography microfluidics. Our work focuses on automating the design of the control layer. We present a method to define an Instruction Set Architecture as a hierarchical composition of flows. From this specification, we automatically infer and generate the logic and signals to control the chip. To complete the design automation of the control layer, we suggest a routing algorithm to connect control channels to peripheral I/O ports. To the microfluidic community, we offer a free computer-aided design tool, Micado, which implements our ideas for automation in a practical plug-in to AutoCAD. We have evaluated our work on real chips and our tool has been used successfully by microfluidic designers.
Description
Thesis (M. Eng.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2009.
Includes bibliographical references (leaves 63-66).
Subjects
Electrical Engineering and Computer Science.
MIT Department
Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science
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reproduction or distribution in any format is prohibited without written
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