ISCB Ebola Award for Important Future Research on the Computational Biology of Ebola Virus
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karp-2015-ISCB Ebola.pdf
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Author(s)
Karp, Peter D.
Berger, Bonnie
Kovats, Diane
Lengauer, Thomas
Linial, Michal
Sabeti, Pardis
Hide, Winston
Rost, Burkhard
Date Issued
January 2015
Journal
PLOS Computational Biology
Publisher
Public Library of Science
Citation
Karp, Peter D., Bonnie Berger, Diane Kovats, Thomas Lengauer, Michal Linial, Pardis Sabeti, Winston Hide, and Burkhard Rost. “ISCB Ebola Award for Important Future Research on the Computational Biology of Ebola Virus.” PLoS Comput Biol 11, no. 1 (January 29, 2015): e1004087.
Version
Final published version
Abstract
Speed is of the essence in combating Ebola; thus, computational approaches should form a significant component of Ebola research. As for the development of any modern drug, computational biology is uniquely positioned to contribute through comparative analysis of the genome sequences of Ebola strains as well as 3-D protein modeling. Other computational approaches to Ebola may include large-scale docking studies of Ebola proteins with human proteins and with small-molecule libraries, computational modeling of the spread of the virus, computational mining of the Ebola literature, and creation of a curated Ebola database. Taken together, such computational efforts could significantly accelerate traditional scientific approaches. In recognition of the need for important and immediate solutions from the field of computational biology against Ebola, the International Society for Computational Biology (ISCB) announces a prize for an important computational advance in fighting the Ebola virus. ISCB will confer the ISCB Fight against Ebola Award, along with a prize of US$2,000, at its July 2016 annual meeting (ISCB Intelligent Systems for Molecular Biology [ISMB] 2016, Orlando, Florida).
MIT Department
Massachusetts Institute of Technology. Department of Mathematics
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DOI of Published Version
https://doi.org/10.1371/journal.pcbi.1004087
