Identification and Manipulation of Memory Engram Cells
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Tone1Liu et al, Final.pdf
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Author(s) • • •
Liu, Xu
Ramirez Moreno, Steve
Tonegawa, Susumu
Redondo, Roger L.
Date Issued
2014
Journal
Cold Spring Harbor Symposia on Quantitative Biology
Publisher
Cold Spring Harbor Laboratory Press
Citation
Liu, Xu, Steve Ramirez, Roger L. Redondo, and Susumu Tonegawa. “Identification and Manipulation of Memory Engram Cells.” Cold Spring Harbor Symposia on Quantitative Biology 79 (2014): 59–65.
Version
Author's final manuscript
Abstract
How memories are formed and stored in the brain remains a fascinating question in neuroscience. Here we discuss the memory engram theory, our recent attempt to identify and manipulate memory engram cells in the brain with optogenetics, and how these methods are used to address questions such as how false memory is formed and how the valence of a memory can be changed in the brain.
MIT Department
Massachusetts Institute of Technology. Department of Biology
Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
Picower Institute for Learning and Memory
RIKEN-MIT Center for Neural Circuit Genetics
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Creative Commons Attribution-Noncommercial-Share Alike
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DOI of Published Version
https://doi.org/10.1101/sqb.2014.79.024901