High-Frequency, Long-Range Coupling Between Prefrontal and Visual Cortex During Attention
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Desimone_High-frequency long-range.pdf
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Author(s)
Gregoriou, Georgia G.
Zhou, Huihui
Desimone, Robert
Gotts, Stephen J.
Date Issued
May 2009
Journal
Science
Publisher
American Association for the Advancement of Science (AAAS)
Citation
Gregoriou, G. G., S. J. Gotts, H. Zhou, and R. Desimone. “High-Frequency, Long-Range Coupling Between Prefrontal and Visual Cortex During Attention.” Science 324, no. 5931 (May 29, 2009): 1207–1210.
Version
Author's final manuscript
Abstract
Electrical recordings in humans and monkeys show attentional enhancement of evoked responses and gamma synchrony in ventral stream cortical areas. Does this synchrony result from intrinsic activity in visual cortex or from inputs from other structures? Using paired recordings in the frontal eye field (FEF) and area V4, we found that attention to a stimulus in their joint receptive field leads to enhanced oscillatory coupling between the two areas, particularly at gamma frequencies. This coupling appeared to be initiated by FEF and was time-shifted by about 8 to 13 milliseconds across a range of frequencies. Considering the expected conduction and synaptic delays between the areas, this time-shifted coupling at gamma frequencies may optimize the postsynaptic impact of spikes from one area upon the other, improving cross-area communication with attention.
MIT Department
McGovern Institute for Brain Research at MIT
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Creative Commons Attribution-Noncommercial-Share Alike
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DOI of Published Version
https://doi.org/10.1126/science.1171402
