Degradation of the Escherichia coli Essential Proteins DapB and Dxr Results in Oxidative Stress, which Contributes to Lethality through Incomplete Base Excision Repair
Name
mbio.03756-21.pdf
Description
Published version
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4.12 MB
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Adobe PDF
Checksum (MD5)
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Author(s) • • • •
Gruber, Charley C
Babu, Vignesh MP
Livingston, Kamren
Joisher, Heer
Walker, Graham C
Date Issued
2022
Journal
mBio
Publisher
American Society for Microbiology
Citation
Gruber, Charley C, Babu, Vignesh MP, Livingston, Kamren, Joisher, Heer and Walker, Graham C. 2022. "Degradation of the Escherichia coli Essential Proteins DapB and Dxr Results in Oxidative Stress, which Contributes to Lethality through Incomplete Base Excision Repair." mBio, 13 (1).
Version
Final published version
Abstract
Bacterial cell death is a poorly understood process. The generation of reactive oxygen species (ROS) is an apparently common response to challenges by a wide variety of lethal stresses, including bactericidal antibiotics.
MIT Department
Massachusetts Institute of Technology. Department of Biology
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Creative Commons Attribution 4.0 International license
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DOI of Published Version
https://doi.org/10.1128/MBIO.03756-21