Measurement of the Time-Resolved Reflection Matrix for Enhancing Light Energy Delivery into a Scattering Medium
Name
Choi-2013-Measurement of the time.pdf
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1.33 MB
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Author(s)
Choi, Youngwoon
Hillman, Timothy Robert
Choi, Wonjun
Lue, Niyom
Choi, Wonshik
Yaqoob, Zahid
Dasari, Ramachandra Rao
So, Peter T. C.
Date Issued
December 2013
Journal
Physical Review Letters
Publisher
American Physical Society
Citation
Choi, Youngwoon, Timothy Hillman, Wonjun Choi, Niyom Lue, Ramachandra Dasari, Peter So, Wonshik Choi, and Zahid Yaqoob. “Measurement of the Time-Resolved Reflection Matrix for Enhancing Light Energy Delivery into a Scattering Medium.” Physical Review Letters 111, no. 24 (December 2013). © 2013 American Physical Society
Version
Final published version
Abstract
Multiple scatterings occurring in a turbid medium attenuate the intensity of propagating waves. Here, we propose a method to efficiently deliver light energy to the desired target depth in a scattering medium. We measure the time-resolved reflection matrix of a scattering medium using coherent time-gated detection. From this matrix, we derive and experimentally implement an incident wave pattern that optimizes the detected signal corresponding to a specific arrival time. This leads to enhanced light delivery at the target depth. The proposed method will lay a foundation for efficient phototherapy and deep-tissue in vivo imaging in the near future.
MIT Department
Massachusetts Institute of Technology. Department of Biological Engineering
Massachusetts Institute of Technology. Department of Chemistry
Massachusetts Institute of Technology. Department of Mechanical Engineering
Massachusetts Institute of Technology. Laser Biomedical Research Center
Massachusetts Institute of Technology. Spectroscopy Laboratory
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Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
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DOI of Published Version
https://doi.org/10.1103/PhysRevLett.111.243901
