Actin cytoskeleton: Thinking globally, actin’ locally
Name
Gertler_Actin cytoskeleton.pdf
Size
61.78 KB
Format
Adobe PDF
Checksum (MD5)
c343e9f7ab50e13b12726cb5f1cceafa
Author(s) •
Lanier, Lorene M.
Gertler, Frank
Date Issued
September 2000
Journal
Current Biology
Publisher
Elsevier
Citation
Lanier, Lorene M., and Frank B. Gertler. “Actin cytoskeleton: Thinking globally, actin’ locally.” Current Biology 10, no. 18 (September 2000): R655-R657. Copyright © 2000 Elsevier Science Ltd.
Version
Final published version
Abstract
A class of proteins dubbed pipmodulins bind to and sequester the phospholipid PIP2 in the plasma membrane. Local release of PIP2 controls actin dynamics in specific subcellular regions and plays a critical role in regulating actin-based cell motility and morphogenesis.
MIT Department
Massachusetts Institute of Technology. Department of Biology
Terms of Use
Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1016/S0960-9822(00)00685-0