A brief review of genome editing technology for generating animal models

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Author(s)
Wang, Haoyi
•
Wu, Sen
•
Capecchi, Mario R.
•
Jaenisch, Rudolf
Date Issued
2020
Journal
Frontiers of Agricultural Science and Engineering
Publisher
Editorial Department of Engineering Sciences
Version
Final published version
Abstract
© The Author(s) 2020. The recent development of genome editing technologies has given researchers unprecedented power to alter DNA sequences at chosen genomic loci, thereby generating various genetically edited animal models. This mini-review briefly summarizes the development of major genome editing tools, focusing on the application of these tools to generate animal models in multiple species.
MIT Department
Massachusetts Institute of Technology. Department of Biology
Terms of Use
Creative Commons Attribution 4.0 International license
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.15302/J-FASE-2019309
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