Review of the Brain’s Behaviour after Injury and Disease for Its Application in an Agent-Based Model (ABM)
Name
biomimetics-09-00362.pdf
Size
1.81 MB
Format
Adobe PDF
Checksum (MD5)
35cb8760d755c0493e494ffec9a8fd87
Author(s)
Irastorza-Valera, Luis
Soria-Gómez, Edgar
Benitez, José María
Montáns, Francisco J.
Saucedo-Mora, Luis
Date Issued
June 14, 2024
Journal
Biomimetics
Publisher
MDPI AG
Citation
Irastorza-Valera, L.; Soria-Gómez, E.; Benitez, J.M.; Montáns, F.J.; Saucedo-Mora, L. Review of the Brain’s Behaviour after Injury and Disease for Its Application in an Agent-Based Model (ABM). Biomimetics 2024, 9, 362.
Version
Final published version
Abstract
The brain is the most complex organ in the human body and, as such, its study entails great challenges (methodological, theoretical, etc.). Nonetheless, there is a remarkable amount of studies about the consequences of pathological conditions on its development and functioning. This bibliographic review aims to cover mostly findings related to changes in the physical distribution of neurons and their connections—the connectome—both structural and functional, as well as their modelling approaches. It does not intend to offer an extensive description of all conditions affecting the brain; rather, it presents the most common ones. Thus, here, we highlight the need for accurate brain modelling that can subsequently be used to understand brain function and be applied to diagnose, track, and simulate treatments for the most prevalent pathologies affecting the brain.
MIT Department
Massachusetts Institute of Technology. Department of Nuclear Science and Engineering
Terms of Use
Creative Commons Attribution
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.3390/biomimetics9060362
