Multi-MHz MEMS-VCSEL swept-source optical coherence tomography for endoscopic structural and angiographic imaging with miniaturized brushless motor probes
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boe-12-4-2384.pdf
Description
Published version
Size
15.74 MB
Format
Adobe PDF
Checksum (MD5)
3dc7cc16182aae3bce85ae3c2d168c91
Author(s)
Zhang, Jason
Nguyen, Tan
Potsaid, Benjamin
Jayaraman, Vijaysekhar
Burgner, Christopher
Chen, Siyu
Li, Jinxi
Liang, Kaicheng
Cable, Alex
Traverso, Giovanni
Date Issued
2021
Journal
Biomedical Optics Express
Publisher
The Optical Society
Citation
Zhang, Jason, Nguyen, Tan, Potsaid, Benjamin, Jayaraman, Vijaysekhar, Burgner, Christopher et al. 2021. "Multi-MHz MEMS-VCSEL swept-source optical coherence tomography for endoscopic structural and angiographic imaging with miniaturized brushless motor probes." Biomedical Optics Express, 12 (4).
Version
Final published version
Abstract
Swept source optical coherence tomography (SS-OCT) enables volumetric imaging of subsurface structure. However, applications requiring wide fields of view (FOV), rapid imaging, and higher resolutions have been challenging because multi-MHz axial scan (A-scan) rates are needed. We describe a microelectromechanical systems vertical cavity surface-emitting laser (MEMS-VCSEL) SS-OCT technology for A-scan rates of 2.4 and 3.0 MHz. Sweep to sweep calibration and resampling are performed using dual channel acquisition of the OCT signal and a Mach Zehnder interferometer signal, overcoming inherent optical clock limitations and enabling higher performance. We demonstrate ultrahigh speed structural SS-OCT and OCT angiography (OCTA) imaging of the swine gastrointestinal tract using a suite of miniaturized brushless motor probes, including a 3.2 mm diameter micromotor OCT catheter, a 12 mm diameter tethered OCT capsule, and a 12 mm diameter widefield OCTA probe. MEMS-VCSELs promise to enable ultrahigh speed SS-OCT with a scalable, low cost, and manufacturable technology, suitable for a diverse range of imaging applications.
MIT Department
Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science
Massachusetts Institute of Technology. Research Laboratory of Electronics
Massachusetts Institute of Technology. Department of Mechanical Engineering
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DOI of Published Version
https://doi.org/10.1364/BOE.420394
