CRISPR-Based Therapeutic Genome Editing: Strategies and In Vivo Delivery by AAV Vectors
Name
nihms-1576523.pdf
Description
Accepted version
Size
965.01 KB
Format
Unknown
Checksum (MD5)
2bc906abcd25b6ed36a643259d599422
Author(s) • •
Wang, Dan
Zhang, Feng
Gao, Guangping
Date Issued
April 2020
Journal
Cell
Publisher
Elsevier BV
Citation
Wang, D, Zhang, F and Gao, G. 2020. "CRISPR-Based Therapeutic Genome Editing: Strategies and In Vivo Delivery by AAV Vectors." Cell, 181 (1).
Version
Author's final manuscript
Abstract
© 2020 Elsevier Inc. Wang, Zhang, and Gao discuss the progress, concerns, and challenges currently facing CRISPR-based therapeutics, a field that has inspired renewed but cautious interest in human genome editing.
MIT Department
Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
Massachusetts Institute of Technology. Department of Biological Engineering
McGovern Institute for Brain Research at MIT
Howard Hughes Medical Institute
Terms of Use
Creative Commons Attribution-NonCommercial-NoDerivs License
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1016/j.cell.2020.03.023