Harnessing the hygroscopic and biofluorescent behaviors of genetically tractable microbial cells to design biohybrid wearables
Name
e1601984.full.pdf
Size
684.94 KB
Format
Adobe PDF
Checksum (MD5)
f2d3ed4e5ad97b26334e288ccd2d3384
Author(s)
Zhou, Kang
Wawrousek, Chris
Petrecca, Katherine
Wang, Wen
Yao, Lining
Cheng, Chin-Yi
Zhang, Teng
Atsumi, Hiroshi
Wang, Luda
Wang, Guanyun
Date Issued
May 2017
Journal
Science Advances
Publisher
American Association for the Advancement of Science (AAAS)
Citation
Wang, Wen et al. “Harnessing the Hygroscopic and Biofluorescent Behaviors of Genetically Tractable Microbial Cells to Design Biohybrid Wearables.” Science Advances 3, 5 (May 2017): e1601984 © 2017 The Authors
Version
Final published version
Abstract
Cells' biomechanical responses to external stimuli have been intensively studied but rarely implemented into devices that interact with the human body. We demonstrate that the hygroscopic and biofluorescent behaviors of living cells can be engineered to design biohybrid wearables, which give multifunctional responsiveness to human sweat. By depositing genetically tractable microbes on a humidity-inert material to form a heterogeneous multilayered structure, we obtained biohybrid films that can reversibly change shape and biofluorescence intensity within a few seconds in response to environmental humidity gradients. Experimental characterization and mechanical modeling of the film were performed to guide the design of a wearable running suit and a fluorescent shoe prototype with bio-flaps that dynamically modulates ventilation in synergy with the body's need for cooling. Keywords: bio-hybrid living actuator; humidity-responsive materials; biofluorescent behaviors; hygroscopic biomaterial pool; genetically-tractable microbial cells; multi-functional wearable devices; body heat; sweat control; ventilation modulation; bio-design
MIT Department
Massachusetts Institute of Technology. Department of Architecture
Massachusetts Institute of Technology. Department of Biological Engineering
Massachusetts Institute of Technology. Department of Chemical Engineering
Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science
Massachusetts Institute of Technology. Department of Mechanical Engineering
Massachusetts Institute of Technology. Media Laboratory
Terms of Use
Attribution-NonCommercial 2.0 Generic (CC BY-NC 2.0)
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1126/SCIADV.1601984
