Microscale Strategies for Generating Cell-Encapsulating Hydrogels
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Selimovic-2012-Microscale strategie.pdf
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3.49 MB
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Author(s)
Selimović, Šeila
Oh, Jonghyun
Bae, Hojae
Dokmeci, Mehmet
Khademhosseini, Ali
Date Issued
September 2012
Journal
Polymers
Publisher
MDPI AG
Citation
Selimović, Šeila, Jonghyun Oh, Hojae Bae, Mehmet Dokmeci, and Ali Khademhosseini. “Microscale Strategies for Generating Cell-Encapsulating Hydrogels.” Polymers 4, no. 4 (September 5, 2012): 1554–1579.
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Final published version
Abstract
Hydrogels in which cells are encapsulated are of great potential interest for tissue engineering applications. These gels provide a structure inside which cells can spread and proliferate. Such structures benefit from controlled microarchitectures that can affect the behavior of the enclosed cells. Microfabrication-based techniques are emerging as powerful approaches to generate such cell-encapsulating hydrogel structures. In this paper we introduce common hydrogels and their crosslinking methods and review the latest microscale approaches for generation of cell containing gel particles. We specifically focus on microfluidics-based methods and on techniques such as micromolding and electrospinning.
MIT Department
Harvard University--MIT Division of Health Sciences and Technology
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Creative Commons Attribution
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DOI of Published Version
https://doi.org/10.3390/polym4031554
