Designing Paper-Based Immunoassays for Biomedical Applications
Name
sensors-19-00554.pdf
Size
3.61 MB
Format
Adobe PDF
Checksum (MD5)
c2420fe8caa537f37af2c0dee5d52f76
Author(s)
Hristov, Delyan R.
Rodriguez-Quijada, Cristina
Hamad-Schifferli, Kimberly
Gomez-Marquez, Jose Zacapa
Date Issued
January 2019
Journal
Sensors
Publisher
Multidisciplinary Digital Publishing Institute (MDPI)
Citation
Hristov, Delyan et al. "Designing Paper-Based Immunoassays for Biomedical Applications." Sensors 19, 3 (January 2019): 554 © 2019 The Authors
Version
Final published version
Abstract
Paper-based sensors and assays have been highly attractive for numerous biological applications, including rapid diagnostics and assays for disease detection, food safety, and clinical care. In particular, the paper immunoassay has helped drive many applications in global health due to its low cost and simplicity of operation. This review is aimed at examining the fundamentals of the technology, as well as different implementations of paper-based assays and discuss novel strategies for improving their sensitivity, performance, or enabling new capabilities. These innovations can be categorized into using unique nanoparticle materials and structures for detection via different techniques, novel biological species for recognizing biomarkers, or innovative device design and/or architecture.
MIT Department
Institute for Medical Engineering and Science
Massachusetts Institute of Technology. Device Research Laboratory
Terms of Use
Creative Commons Attribution
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.3390/s19030554
