Engineering Engineering Hyperthermostable rcSso7d as Reporter Molecule for in Vitro Diagnostic Tests
Name
c8me00049b.pdf
Size
1.5 MB
Format
Adobe PDF
Checksum (MD5)
444c5b1a4aa54cc163a569bcc37fc6ac
Author(s)
Sung, Ki-Joo
Miller, Eric Alexander
Sikes Johnson, Hadley
Date Issued
October 2018
Journal
Molecular Systems Design & Engineering
Publisher
Royal Society of Chemistry (RSC)
Citation
Sung, Ki-Joo et al. “Engineering Hyperthermostable rcSso7d as Reporter Molecule for in Vitro Diagnostic Tests.” Molecular Systems Design & Engineering 2018, 5 (October 2018) © 2018 Royal Society of Chemistry
Version
Final published version
Abstract
The hyperthermostable binding scaffold, rcSso7d, has recently been studied for use in in vitro diagnostic tests but has not yet been demonstrated as a soluble reporter protein. Here, we investigated several rcSso7d protein constructs and biotin conjugation methods to link a detectable signal to the presence of a target biomarker.
MIT Department
Massachusetts Institute of Technology. Department of Chemical Engineering
Terms of Use
Creative Commons Attribution-NonCommercial 3.0 Unported
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1039/C8ME00049B
