Roadmap on biology in time varying environments
Name
Murugan_2021_Phys._Biol._18_041502.pdf
Description
Published version
Size
6 MB
Format
Adobe PDF
Checksum (MD5)
5a4ec35869e677cfc5d875616a904a3a
Author(s)
Murugan, Arvind
Husain, Kabir
Rust, Michael J
Hepler, Chelsea
Bass, Joseph
Pietsch, Julian MJ
Swain, Peter S
Jena, Siddhartha G
Toettcher, Jared E
Chakraborty, Arup K
Date Issued
2021
Journal
Physical Biology
Publisher
IOP Publishing
Version
Final published version
Abstract
Biological organisms experience constantly changing environments, from sudden changes in physiology brought about by feeding, to the regular rising and setting of the Sun, to ecological changes over evolutionary timescales. Living organisms have evolved to thrive in this changing world but the general principles by which organisms shape and are shaped by time varying environments remain elusive. Our understanding is particularly poor in the intermediate regime with no separation of timescales, where the environment changes on the same timescale as the physiological or evolutionary response. Experiments to systematically characterize the response to dynamic environments are challenging since such environments are inherently high dimensional. This roadmap deals with the unique role played by time varying environments in biological phenomena across scales, from physiology to evolution, seeking to emphasize the commonalities and the challenges faced in this emerging area of research.
MIT Department
Massachusetts Institute of Technology. Department of Chemical Engineering
Massachusetts Institute of Technology. Department of Physics
Massachusetts Institute of Technology. Department of Chemistry
Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Ragon Institute of MGH, MIT and Harvard
Terms of Use
Creative Commons Attribution 4.0 International license
Persistent DSpace Link
DOI of Published Version
10.1088/1478-3975/abde8d
https://doi.org/10.1088/1478-3975/abde8d
