Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
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Gehrke_Multicolored silver.pdf
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Author(s) • • • • •
Yen, Chun-Wan
de Puig Guixe, Helena
Tam, Justina
Bosch, Irene
Gehrke, Lee
Hamad-Schifferli, Kimberly
Date Issued
February 2015
Journal
Lab on a Chip
Publisher
Royal Society of Chemistry
Citation
Yen, Chun-Wan, Helena de Puig, Justina O. Tam, Jose Gomez-Marquez, Irene Bosch, Kimberly Hamad-Schifferli and Lee Gehrke. "Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses." Lab Chip, 2015,15, 1638-1641.
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Author's final manuscript
Abstract
Rapid point-of-care (POC) diagnostic devices are needed for field-forward screening of severe acute systemic febrile illnesses. Multiplexed rapid lateral flow diagnostics have the potential to distinguish among multiple pathogens, thereby facilitating diagnosis and improving patient care. Here, we present a platform for multiplexed pathogen detection using multi-colored silver nanoplates. This design requires no external excitation source and permits multiplexed analysis in a single channel, facilitating integration and manufacturing.
MIT Department
Little Devices @ MIT
MIT-SUTD Collaboration Office
Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Lincoln Laboratory
Massachusetts Institute of Technology. Department of Mechanical Engineering
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DOI of Published Version
https://doi.org/10.1039/c5lc00055f