Untethered muscle tracking using magnetomicrometry
Name
fbioe-10-1010275.pdf
Description
Published version
Size
2.18 MB
Format
Adobe PDF
Checksum (MD5)
d124063ad4d39d388c8653b3402caf93
Author(s)
Taylor, Cameron R
Yeon, Seong Ho
Clark, William H
Clarrissimeaux, Ellen G
O’Donnell, Mary Kate
Roberts, Thomas J
Herr, Hugh M
Date Issued
2022
Journal
Frontiers in Bioengineering and Biotechnology
Publisher
Frontiers Media SA
Citation
Taylor, Cameron R, Yeon, Seong Ho, Clark, William H, Clarrissimeaux, Ellen G, O’Donnell, Mary Kate et al. 2022. "Untethered muscle tracking using magnetomicrometry." Frontiers in Bioengineering and Biotechnology, 10.
Version
Final published version
Abstract
Muscle tissue drives nearly all movement in the animal kingdom, providing power, mobility, and dexterity. Technologies for measuring muscle tissue motion, such as sonomicrometry, fluoromicrometry, and ultrasound, have significantly advanced our understanding of biomechanics. Yet, the field lacks the ability to monitor muscle tissue motion for animal behavior outside the lab. Towards addressing this issue, we previously introduced magnetomicrometry, a method that uses magnetic beads to wirelessly monitor muscle tissue length changes, and we validated magnetomicrometry via tightly-controlled in situ testing. In this study we validate the accuracy of magnetomicrometry against fluoromicrometry during untethered running in an in vivo turkey model. We demonstrate real-time muscle tissue length tracking of the freely-moving turkeys executing various motor activities, including ramp ascent and descent, vertical ascent and descent, and free roaming movement. Given the demonstrated capacity of magnetomicrometry to track muscle movement in untethered animals, we feel that this technique will enable new scientific explorations and an improved understanding of muscle function.
MIT Department
Massachusetts Institute of Technology. Media Laboratory
Terms of Use
Creative Commons Attribution 4.0 International license
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.3389/fbioe.2022.1010275
