For T Cell Receptors, Some Breakups Might Not Last Forever
Name
Govern-2010-For T Cell Receptors.pdf
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114.37 KB
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Author(s)
Govern, Christopher C.
Chakraborty, Arup K.
Date Issued
February 2010
Journal
Immunity
Publisher
Elsevier B.V.
Citation
Govern, Christopher C., and Arup K. Chakraborty. “For T Cell Receptors, Some Breakups Might Not Last Forever.” Immunity 32, no. 2 (February 2010): 141–142. © 2010 Elsevier B.V.
Version
Final published version
Abstract
Does the affinity or half-life of peptide-MHC-T cell receptor (TCR) interactions determine T cell activation? In this issue of Immunity, Aleksic et al. (2010) propose a role for the on rate through multiple rebindings to the same TCR.
MIT Department
Institute for Medical Engineering and Science
Massachusetts Institute of Technology. Department of Biological Engineering
Massachusetts Institute of Technology. Department of Chemical Engineering
Massachusetts Institute of Technology. Department of Chemistry
Ragon Institute of MGH, MIT and Harvard
Terms of Use
Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
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DOI of Published Version
https://doi.org/10.1016/j.immuni.2010.02.005
