Neuroprotection and acidosis induced by cortical spreading depression
Name
Kwong-2016-Neuroprotection and acidosis induce.pdf
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250.28 KB
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Adobe PDF
Checksum (MD5)
18a651e3ba7e4aa56e6ce4f2660d5dd9
Author(s)
Chan, Suk-tak
Kwong, Kenneth K
Date Issued
December 2016
Journal
Neuropsychiatric Disease and Treatment
Publisher
Dove Medical Press
Citation
Kwong, Kenneth, and Suk-tak Chan. “Neuroprotection and Acidosis Induced by Cortical Spreading Depression.” Neuropsychiatric Disease and Treatment Volume 12 (2016): 3191–3194.
Version
Final published version
Abstract
We read with interest the article “Cortical spreading depression produces a neuroprotective effect activating mitochondrial uncoupling protein-5” published in Neuropsychiatr Dis Treat by Viggiano et al.1 The authors showed that cerebral spreading depression (CSD) triggered uncoupling protein-5 (UCP-5),1 which had been reported to exert a long-term effect upon neuron protection.2 The result is another piece in CSD literature on modifying gene expressions to provide neuroprotection to subsequent ischemic episodes.3,4
MIT Department
Harvard University--MIT Division of Health Sciences and Technology
Terms of Use
Creative Commons Attribution-NonCommercial 3.0 Unported
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DOI of Published Version
https://doi.org/10.2147/ndt.s125677
