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  4. Orientation-Specific Attachment of Polymeric Microtubes on Cell Surfaces

Orientation-Specific Attachment of Polymeric Microtubes on Cell Surfaces

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Author(s)
Gilbert, Jonathan Brian
•
O'Brien, Janice S.
•
Suresh, Harini S.
•
Cohen, Robert E.
•
Rubner, Michael F.
Date Issued
November 2013
Journal
Advanced Materials
Publisher
WILEY-VCH Verlag GmbH & Co.
Citation
Gilbert, J. B., O'Brien, J. S., Suresh, H. S., Cohen, R. E. and Rubner, M. F. (2013), Orientation-Specific Attachment of Polymeric Microtubes on Cell Surfaces. Adv. Mater., 25: 5948–5952.
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Author's final manuscript
Abstract
Tubular particles presenting heterogeneous regions of chemistry on the tube-ends versus the side are fabricated and are shown to control the particle orientation on the surface of live lymphocytes. Controlling the orientation of anisotropic microparticles on cell surfaces is of interest for biomedical applications and drug delivery in particular, since it can be used to promote or resist particle internalization.
MIT Department
Massachusetts Institute of Technology. Department of Chemical Engineering
Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science
Massachusetts Institute of Technology. Department of Materials Science and Engineering
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Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
Persistent DSpace Link
http://hdl.handle.net/1721.1/88976
DOI of Published Version
https://doi.org/10.1002/adma.201302673
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