7.342 The Biology of Aging: Age-Related Diseases and Interventions, Fall 2011
Author(s) •
Lamming, Dudley W.
Bell, Eric L.
Alternative Title
The Biology of Aging: Age-Related Diseases and Interventions
Date Issued
December 2011
Abstract
Aging involves an intrinsic and progressive decline in function that eventually will affect us all. While everyone is familiar with aging, many basic questions about aging are mysterious. Why are older people more likely to experience diseases like cancer, stroke, and neurodegenerative disorders? What changes happen at the molecular and cellular levels to cause the changes that we associate with old age? Is aging itself a disease, and can we successfully intervene in the aging process?This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching.
Subjects
Aging
age-related diseases
molecular biology of aging
calorie restriction
resveratrol
rapamycin
Caloric restriction (CR)
Cellular senescence
telomerase
progeroid syndromes
mitochondrial DNA
yeast
C. elegans
Drosophila
Sirtuins
SIR4
target of rapamycin (TOR)
oxidative damage
Reactive oxygen species (ROS)
National Institute on Aging Interventions Testing Program
Alzheimer’s disease
MIT Department
Massachusetts Institute of Technology. Department of Biology
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