Ex vivo Imaging of Human Pathologies with Integrated Optical Coherence Tomography (OCT) and Optical Coherence Microscopy (OCM)
Name
Zhou-2009-Ex vivo Imaging of Human Pathologies with Integrated Optical Coherence Tomography.pdf
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1.46 MB
Format
Adobe PDF
Checksum (MD5)
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Author(s)
Bryan, Bradley
Wang, Yihong
Connolly, James L.
Zhou, Chao
Aguirre, Aaron Dominic
Tsai, Tsung-Han
Fujimoto, James G.
Date Issued
February 2009
Journal
Proceedings of the Society of Photo-optical Instrumentation Engineers
Publisher
Society of Photo-optical Instrumentation Engineers
Citation
Zhou, Chao et al. “Ex vivo imaging of human pathologies with integrated optical coherence tomography (OCT) and optical coherence microscopy (OCM).” Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XIII. Ed. James G. Fujimoto, Joseph A. Izatt, & Valery V. Tuchin. San Jose, CA, USA: SPIE, 2009. 71680N-8. © 2009 Society of Photo-optical Instrumentation Engineers.
Version
Final published version
Abstract
We report an imaging study using integrated 3D-OCT and OCM for the assessment of various human thyroid and breast pathologies. The 3D-OCT data sets enable en face projection imaging, which provides large field of view with uniform focus and signal level, while OCM provides high magnification that enables cellular resolution imaging. We have demonstrated that the integrated 3D-OCT and OCM technology provide a substantial improvement over standard OCT for the visualization of tissue pathology and can serve as a useful imaging tool in the clinical settings.
MIT Department
Harvard University--MIT Division of Health Sciences and Technology
Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science
Massachusetts Institute of Technology. Research Laboratory of Electronics
Terms of Use
Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
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DOI of Published Version
http://dx.doi.org/10.1117/12.809064
