Bubble-induced damping in displacement-driven microfluidic flows
Name
Lee-2012-Bubble-induced damping in displacement-driven microfluidic flows.pdf
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1.83 MB
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Author(s)
Lee, Jongho
Rahman, Faizur
Laoui, Tahar
Karnik, Rohit
Date Issued
August 2012
Journal
Physical Review E
Publisher
American Physical Society
Citation
Lee, Jongho et al. “Bubble-induced Damping in Displacement-driven Microfluidic Flows.” Physical Review E 86.2 (2012). ©2012 American Physical Society
Version
Final published version
Abstract
Bubble damping in displacement-driven microfluidic flows was theoretically and experimentally investigated for a Y-channel microfluidic network. The system was found to exhibit linear behavior for typical microfluidic flow conditions. The bubbles induced a low-pass filter behavior with a characteristic cutoff frequency that scaled proportionally with flow rate and inversely with bubble volume and exhibited a minimum with respect to the relative resistances of the connecting channels. A theoretical model based on the electrical circuit analogy was able to predict experimentally observed damping of fluctuations with excellent agreement. Finally, a flowmeter with high resolution (0.01 μL/min) was demonstrated as an application of the bubble-aided stabilization. This study may aid in the design of many other bubble-stabilized microfluidic systems.
MIT Department
Massachusetts Institute of Technology. Department of Mechanical Engineering
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Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
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DOI of Published Version
https://doi.org/10.1103/PhysRevE.86.026301
