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Structural and biophysical insights into the mode of covalent binding of rationally designed potent BMX inhibitors
Name
d0cb00033g.pdf
Description
Published version
Size
3.44 MB
Format
Adobe PDF
Checksum (MD5)
d26271baac720609d643f1f28c8f083c
Author(s) • • • • • • • • •
Seixas, João D
Sousa, Bárbara B
Marques, Marta C
Guerreiro, Ana
Traquete, Rui
Rodrigues, Tiago
Albuquerque, Inês S
Sousa, Marcos FQ
Lemos, Ana R
Sousa, Pedro MF
Date Issued
2020
Journal
RSC Chemical Biology
Publisher
Royal Society of Chemistry (RSC)
Citation
Seixas, João D, Sousa, Bárbara B, Marques, Marta C, Guerreiro, Ana, Traquete, Rui et al. 2020. "Structural and biophysical insights into the mode of covalent binding of rationally designed potent BMX inhibitors." RSC Chemical Biology, 1 (4).
Version
Final published version
Abstract
We identified potent, functionalisable BMX inhibitors and revealed their covalent mode of binding to BMX by X-ray crystallography.
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Creative Commons Attribution 4.0 International license
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DOI of Published Version
10.1039/D0CB00033G