Ultra-High Resolution Optical Coherence Tomography Imaging of Unilateral Drusen in a 31 Year Old Woman
Author(s)
de Carlo, Talisa E.
Adhi, Mehreen
Lu, Chen David
Duker, Jay S.
Fujimoto, James G
Waheed, Nadia K.
Date Issued
October 2015
Journal
Clinical Medical Reviews and Case Reports
Publisher
ClinMed International Library
Citation
de Carlo Talisa E. et al. "Ultra-High Resolution Optical Coherence Tomography Imaging of Unilateral Drusen in a 31 Year Old Woman." Clinical Medical Reviews and Case Reports 2, 10 (October 2015): CMRCR-2-063 © 2015 The Authors
Version
Final published version
Abstract
We report a case of widespread unilateral drusen in a healthy 31 year old Caucasian woman using multi-modal imaging including ultra-high resolution optical coherence tomography (UHR-OCT). Dilated fundus exam showed multiple drusen-like lesions in the posterior pole without heme or fluid. Fundus auto fluorescence demonstrated hyperautofluorescent at the deposits. Fluorescein angiography revealed mild hyperfluorescence and staining of the lesions. Spectral-domain optical coherence tomography (SD-OCT) OS showed accumulations in the temporal macula at Bruch's membrane. UHR-OCT provided improved axial resolution compared to the standard 5 μm on the commercial SD-OCT and confirmed the presence of deposits in Bruch's membrane, consistent with drusen. The retinal layers were draped over the excrescences but did not show any disruption. Keywords: Drusen; Optical Coherence Tomography; Retinal Imaging; Retina
MIT Department
Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science
Massachusetts Institute of Technology. Research Laboratory of Electronics
Terms of Use
Creative Commons Attribution 4.0 International license
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.23937/2378-3656/1410063
