Neurobiology of social behavior abnormalities in autism and Williams syndrome
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nihms788653.pdf
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Author(s)
Barak, Boaz
Feng, Guoping
Date Issued
April 2016
Journal
Nature Neuroscience
Publisher
Nature Publishing Group
Citation
Barak, Boaz, and Feng, Guoping. “Neurobiology of Social Behavior Abnormalities in Autism and Williams Syndrome.” Nature Neuroscience 19, 6 (April 2016): 647–655 © 2016 Nature America, Inc
Version
Author's final manuscript
Abstract
Social behavior is a basic behavior mediated by multiple brain regions and neural circuits, and is crucial for the survival and development of animals and humans. Two neuropsychiatric disorders that have prominent social behavior abnormalities are autism spectrum disorders (ASD), which is characterized mainly by hyposociability, and Williams syndrome (WS), whose subjects exhibit hypersociability. Here we review the unique properties of social behavior in ASD and WS, and discuss the major theories in social behavior in the context of these disorders. We conclude with a discussion of the research questions needing further exploration to enhance our understanding of social behavior abnormalities.
MIT Department
Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
McGovern Institute for Brain Research at MIT
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Creative Commons Attribution-Noncommercial-Share Alike
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DOI of Published Version
https://doi.org/10.1038/NN.4276
