Ex Vivo and In Vivo Imaging Study of Ultrasound Capsule Endoscopy
Name
med_014_02_021005.pdf
Description
Published version
Size
1.97 MB
Format
Adobe PDF
Checksum (MD5)
173c366bc3832f082824448db615f6ac
Author(s)
Lee, John Haeseon
Traverso, Carlo Giovanni
Ibarra Zarate, David
Boning, Duane S
Anthony, Brian
Date Issued
March 2020
Journal
Journal of Medical Devices
Publisher
ASME International
Citation
Lee, John H. et al. "Ex Vivo and In Vivo Imaging Study of Ultrasound Capsule Endoscopy." Journal of Medical Devices 14, 2 (March 2020): 021005 © 2020 BMJ Publishing Group
Version
Final published version
Abstract
Wireless capsule endoscopy (WCE) has revolutionized the capacity for evaluation of the gastrointestinal (GI) tract, but its evaluation is limited to the mucosal surface. To overcome this, ultrasound capsule endoscopy (UCE) that can evaluate the deeper structures beyond the mucosal surface has been proposed and several studies focusing on technology development have demonstrated promising results. However, investigations of the potential for clinical utility of this technology are lacking. This work had two main goals: perform ex vivo and in vivo imaging studies in a swine model to (1) evaluate if acoustic coupling between a capsule with a specific size and GI tract can be achieved only through peristalsis autonomously without any human control and (2) identify key issues and challenges to help guide further research. The images acquired in these studies were able to visualize the wall of the GI tract as well as the structures within demonstrating that achieving adequate acoustic coupling through peristalsis is possible. Critical challenges were identified including level of visualization and area of coverage; these require further in-depth investigation before potential clinical utility of UCE technology can be concluded.
MIT Department
Massachusetts Institute of Technology. Department of Mechanical Engineering
Terms of Use
Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1115/1.4046352
