A once-a-month oral contraceptive
Name
Once-a-month-contraceptive combined files.pdf
Description
Accepted version
Size
2.77 MB
Format
Adobe PDF
Checksum (MD5)
4ab3fd6cf4d5bc9e4292575b2f2e8d91
Author(s)
Kirtane, Ameya R.
Hua, Tiffany
Hayward, Alison
Wahane, Aniket Vijay
Lopes, Aaron
Bensel, Taylor
Brooks, Sierra
Gwynne, Declan
Wainer, Jacob
Collins, Joy
Date Issued
December 2019
Journal
Science Translational Medicine
Publisher
American Association for the Advancement of Science (AAAS)
Citation
Kirtane, Ameya R. et al. “A once-a-month oral contraceptive.” Science Translational Medicine, 11, 521 (December 2019): eaay2602 © 2019 The Author(s)
Version
Author's final manuscript
Abstract
Poor patient adherence to oral contraceptives is the predominant cause of failure of these therapies, leading to unplanned pregnancies that can negatively affect female health worldwide. To improve patient adherence, we developed an oral contraceptive that is administered once a month. Here, we describe the design and report in vivo characterization of a levonorgestrel-releasing gastric resident dosage form in pigs.
MIT Department
Massachusetts Institute of Technology. Department of Chemical Engineering
Massachusetts Institute of Technology. Division of Comparative Medicine
Massachusetts Institute of Technology. Media Laboratory
Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Massachusetts Institute of Technology. Department of Mechanical Engineering
Koch Institute for Integrative Cancer Research at MIT
Terms of Use
Creative Commons Attribution-Noncommercial-Share Alike
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1126/SCITRANSLMED.AAY2602
