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  5. Multi-scale quantitative elastography and its application to blood pressure estimation

Multi-scale quantitative elastography and its application to blood pressure estimation

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880139475-MIT.pdf

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Author(s)
Zakrzewski, Aaron Michael
Advisor(s)
Brian W. Anthony.
Date Issued
2013
Publisher
Massachusetts Institute of Technology
Abstract
Elastography is a method that can be used to measure the elasticity of soft biological tissue and, ultimately, to detect cancerous tumors. In this thesis, quantitative compression based ultrasound elastography is developed using a fast multi-scale approach. The inverse problem optimization methods of elastography are applied to estimate noninvasively the arterial wall stiffness of a vessel as well as blood pressure. Simulation and experimental results are presented that predict the accuracy of the methods. A method is also introduced to eliminate the need for a reference pressure during the optimization over blood pressure. Using ultrasound, these techniques could provide noninvasive continuous measurement of blood pressure in major arteries and could give doctors another way to gather information about a patients cardiovascular health.
Description
Thesis: S.M., Massachusetts Institute of Technology, Department of Mechanical Engineering, 2013.
Cataloged from PDF version of thesis.
Includes bibliographical references (pages 113-119).
Subjects
Mechanical Engineering.
MIT Department
Massachusetts Institute of Technology. Department of Mechanical Engineering
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M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission.
http://dspace.mit.edu/handle/1721.1/7582
Persistent DSpace Link
http://hdl.handle.net/1721.1/87919
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