Remote-Controlled Mice
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Anikeeva_Remote-controlled mice.pdf
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Author(s) •
Anikeeva, Polina Olegovna
Jia, Xiaoting
Date Issued
August 2015
Journal
Cell Systems
Publisher
Elsevier
Citation
Anikeeva, Polina, and Jia, Xiaoting. “Remote-Controlled Mice.” Cell Systems 1, 2 (August 2015): 104–105 © 2015 Elsevier
Version
Author's final manuscript
Abstract
What if expression of a light-sensitive protein could be triggered wirelessly, on demand? What if optogenetics and neuropharmacology could be implemented in an untethered, freely moving animal model? Such technology would allow for a plethora of neurobiological experiments that are currently confounded by repeated animal handling, tissue-damaging cannulas, and tangled optical cables. In the July 30 issue of Cell, Jeong and colleagues introduce such a technology. The ultrathin and flexible devices, termed wireless optofluidic probes, enable remote control of drug infusion and optical manipulation in the deep-brain regions of freely moving mice engaged in behavioral tasks
MIT Department
Massachusetts Institute of Technology. Department of Materials Science and Engineering
Massachusetts Institute of Technology. Research Laboratory of Electronics
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Creative Commons Attribution-NonCommercial-NoDerivs License
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DOI of Published Version
https://doi.org/10.1016/J.CELS.2015.08.005