Brain Mechanisms of Change in Addiction Treatment: Models, Methods, and Emerging Findings
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Author(s)
Chung, Tammy
Noronha, Antonio
Carroll, Kathleen M.
Potenza, Marc N.
Hutchison, Kent
Calhoun, Vince D.
Morgenstern, Jon
Nixon, Sara Jo
Wexler, Bruce E.
Brewer, Judson
Date Issued
July 2016
Journal
Current Addiction Reports
Publisher
Springer International Publishing
Citation
Chung, Tammy, Antonio Noronha, Kathleen M. Carroll, Marc N. Potenza, Kent Hutchison, Vince D. Calhoun, John D. E. Gabrieli, et al. “Brain Mechanisms of Change in Addiction Treatment: Models, Methods, and Emerging Findings.” Current Addiction Reports 3, no. 3 (July 9, 2016): 332–342.
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Author's final manuscript
Abstract
Purpose of review
Increased understanding of “how” and “for whom” treatment works at the level of the brain has potential to transform addiction treatment through the development of innovative neuroscience-informed interventions. The 2015 Science of Change meeting bridged the fields of neuroscience and psychotherapy research to identify brain mechanisms of behavior change that are “common” across therapies and “specific” to distinct behavioral interventions.
Recent findings
Conceptual models of brain mechanisms underlying cognitive behavioral therapy, mindfulness interventions, and motivational interviewing differ in targeting brain circuits representing “top-down” cognitive control and “bottom-up” processing of reward. Methods for integrating neuroimaging into psychotherapy research can reveal recovery of brain functioning with sustained abstinence, which may be facilitated by psychotherapy and cognitive training.
Summary
Neuroimaging provides powerful tools for determining brain mechanisms underlying treatment effects, predicting and monitoring outcomes, developing novel neuroscience-informed interventions, and identifying for whom an intervention will be effective.
MIT Department
Harvard University--MIT Division of Health Sciences and Technology
McGovern Institute for Brain Research at MIT
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DOI of Published Version
https://doi.org/10.1007/s40429-016-0113-z
