Surgical system for image-based stereotaxy in the rat
Name
62587894-MIT.pdf
Description
Full printable version
Size
4.32 MB
Format
Adobe PDF
Checksum (MD5)
6a55f2efa4f6c6547888373caada8977
Author(s)
Cosman, Niels Johnson
Advisor(s)
Eric R. Cosman.
Date Issued
2005
Publisher
Massachusetts Institute of Technology
Abstract
Currently there are no of MRI image-based stereotactic apparatus for target determination in the brain of animals. Until now, the only stereotactic devices for directing problems and electrodes in animal brains for neuroscience are based on dental and ear canal fixation and on skull based features which are at best crudely related to brain anatomy. As a result there is no accurate method or apparatus to place a probe into the brain of a research animal. Proposed here is a surgical system to replace these outmoded techniques. The system consists of a MR compatible head frame and a MR localizer designed specifically for the Norway species of rat. This system allows for accurate targeting of structures within the rodent brain and precision placement of electrodes to these structures. This system utilizes the most current MRI imaging technologies available to provide major improvements to quality and reliability in neuroscience data acquisition.
Description
Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2005.
Includes bibliographical references (leaf 41).
Subjects
Mechanical Engineering.
MIT Department
Massachusetts Institute of Technology. Department of Mechanical Engineering
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