Cell Rover—a miniaturized magnetostrictive antenna for wireless operation inside living cells
Name
s41467-022-32862-4.pdf
Description
Published version
Size
3.44 MB
Format
Adobe PDF
Checksum (MD5)
3cb947053ff9710d87173779f3dbab89
Author(s)
Joy, Baju
Cai, Yubin
Bono, David C
Sarkar, Deblina
Date Issued
September 22, 2022
Journal
Nature Communications
Publisher
Springer Science and Business Media LLC
Citation
Joy, Baju, Cai, Yubin, Bono, David C and Sarkar, Deblina. 2022. "Cell Rover—a miniaturized magnetostrictive antenna for wireless operation inside living cells." Nature Communications, 13 (1).
Version
Final published version
Abstract
AbstractAn intracellular antenna can open up new horizons for fundamental and applied biology. Here, we introduce the Cell Rover, a magnetostrictive antenna which can operate wirelessly inside a living cell and is compatible with 3D biological systems. It is sub-mm in size, acoustically actuated by an AC magnetic field and resonantly operated at low MHz frequencies, which is ideal for living systems. We developed an injection scheme involving non-uniform magnetic fields for intracellular injection of the Cell Rovers and demonstrated their operation in fully opaque, stage VI Xenopus oocytes, for which real-time imaging with conventional technologies is challenging. We also show that they provide a pathway for multiplexing applications to individually address multiple cells or to tune to more than one antenna within the same cell for versatile functionalities. This technology forms the foundation stone that can enable the integration of future capabilities such as smart sensing, modulation as well as energy harvesting to power in-cell nanoelectronic computing and can potentially bring the prowess of information technology inside a living cell. This could lead to unprecedented opportunities for fundamental understanding of biology as well as diagnostics and therapeutics.
MIT Department
Massachusetts Institute of Technology. Media Laboratory
Massachusetts Institute of Technology. Department of Materials Science and Engineering
Terms of Use
Creative Commons Attribution 4.0 International license
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1038/s41467-022-32862-4
