Role of drug delivery technologies in the success of COVID-19 vaccines: a perspective
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13346_2022_1146_ReferencePDF.pdf
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439.9 KB
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Author(s)
Labouta, Hagar I.
Langer, Robert
Cullis, Pieter R.
Merkel, Olivia M.
Prausnitz, Mark R.
Gomaa, Yasmine
Nogueira, Sara S.
Kumeria, Tushar
Date Issued
March 15, 2022
Publisher
Springer US
Citation
Labouta, Hagar I., Langer, Robert, Cullis, Pieter R., Merkel, Olivia M., Prausnitz, Mark R. et al. 2022. "Role of drug delivery technologies in the success of COVID-19 vaccines: a perspective."
Version
Author's final manuscript
Abstract
Abstract
The triumphant success of mRNA vaccines is a testimony to the important role drug delivery technologies have played in protecting billions of people against SARS-CoV-2 (or the Corona Virus Disease 2019; COVID-19). Several lipid nanoparticle (LNP) mRNA vaccines were developed and have been instrumental in preventing the disease by boosting the immune system against the pathogen, SARS-CoV-2. These vaccines have been built on decades of scientific research in drug delivery of mRNA, vaccines, and other biologicals. In this manuscript, several leading and emerging scientists in the field of drug delivery share their perspective on the role of drug delivery technologies in developing safe and efficacious vaccines, in a roundtable discussion. The authors also discussed their viewpoint on the current challenges, and the key research questions that should drive this important area of research.
MIT Department
Massachusetts Institute of Technology. Department of Chemical Engineering
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Creative Commons Attribution-Noncommercial-Share Alike
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DOI of Published Version
https://doi.org/10.1007/s13346-022-01146-1
