Design and development of a 3D X-ray microscope
Name
76838137-MIT.pdf
Description
Full printable version
Size
19.48 MB
Format
Adobe PDF
Checksum (MD5)
bcef187745063e67cb4772d5b480110a
Author(s)
Brayanov, Jordan, 1981-
Advisor(s)
Ian W. Hunter.
Alternative Title
Design and development of a three-dimensional X-ray microscope
Date Issued
2006
Publisher
Massachusetts Institute of Technology
Abstract
The rapid development of needle-free injection systems demands better and faster imaging systems, capable of imaging the transient and steady state response of an injection into real tissue. X-ray radiography, x-ray microscopy, and computerized tomography (CT) were identified as the most appropriate imaging techniques used for non-invasive imaging of opaque objects and an instrument was constructed, utilizing all of those techniques. The instrument was capable of producing x-ray radiographies with native resolution of less than 30 [mu]m, frame rate of 32 frames per second and a field of view of 30 mm by 40 mm. Using magnifying cone-beam x-ray source the ultimate resolution of the system exceeded 5 [mu]m, while maintaining image sharpness and clarity. Digital image reconstruction techniques, based on the inverse Radon transformation and the Fourier slice theorem were used to regenerate conventional CT images as well as contrast volumetric 3D images of the internal structures of opaque objects. This paper presents the design and development of the 3D x-ray microscope together with experimental results obtained during the calibration and initial testing of the instrument.
Description
Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2006.
Includes bibliographical references (leaves 115-117).
Subjects
Mechanical Engineering.
MIT Department
Massachusetts Institute of Technology. Department of Mechanical Engineering
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