Turning omics data into therapeutic insights
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Fraenkel-draft5_6-16_revisions.pdf
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Author(s)
Kedaigle, Amanda Joy
Fraenkel, Ernest
Date Issued
August 2018
Journal
Current Opinion in Pharmacology
Publisher
Elsevier
Citation
Kedaigle, Amanda, and Ernest Fraenkel. “Turning Omics Data into Therapeutic Insights.” Current Opinion in Pharmacology, vol. 42, Oct. 2018, pp. 95–101.
Version
Author's final manuscript
Abstract
Omics technologies have made it easier and cheaper to evaluate thousands of biological molecules at once. These advances have led to novel therapies approved for use in the clinic, elucidated the mechanisms behind disease-associated mutations, led to increased accuracy in disease subtyping and personalized medicine, and revealed novel uses and treatment regimes for existing drugs through drug repurposing and pharmacology studies. In this review, we summarize some of these milestones and discuss the potential of integrative analyses that combine multiple data types for further advances.
MIT Department
Massachusetts Institute of Technology. Department of Biological Engineering
Terms of Use
Creative Commons Attribution-NonCommercial-NoDerivs License
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1016/j.coph.2018.08.006
