Setting Our Sights on Infectious Diseases
Name
acsinfecdis.9b00371.pdf
Description
Published version
Size
622.31 KB
Format
Adobe PDF
Checksum (MD5)
5f3a424c33a26e2a0f29dc42f378405c
Author(s)
De Rycker, Manu
Horn, David
Aldridge, Bree
Amewu, Richard K.
Barry, Clifton E.
Buckner, Frederick S.
Cook, Sarah
Ferguson, Michael A. J.
Gobeau, Nathalie
Herrmann, Jennifer
Date Issued
December 2019
Journal
ACS Infectious Diseases
Publisher
American Chemical Society (ACS)
Citation
De Rycker, Manu et al. "Setting Our Sights on Infectious Diseases." ACS Infectious Diseases 6, 1 (December 2019): 3–13 © 2019 American Chemical Society
Version
Final published version
Abstract
In May 2019, the Wellcome Centre for Anti-Infectives Research (WCAIR) at the University of Dundee, UK, held an international conference with the aim of discussing some key questions around discovering new medicines for infectious diseases and a particular focus on diseases affecting Low and Middle Income Countries. There is an urgent need for new drugs to treat most infectious diseases. We were keen to see if there were lessons that we could learn across different disease areas and between the preclinical and clinical phases with the aim of exploring how we can improve and speed up the drug discovery, translational, and clinical development processes. We started with an introductory session on the current situation and then worked backward from clinical development to combination therapy, pharmacokinetic/pharmacodynamic (PK/PD) studies, drug discovery pathways, and new starting points and targets. This Viewpoint aims to capture some of the learnings.
MIT Department
Massachusetts Institute of Technology. Department of Civil and Environmental Engineering
Terms of Use
Creative Commons Attribution 4.0 International license
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1021/acsinfecdis.9b00371
