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  4. IGFBP3 and T1D: Systemic Factors in Colonic Stem Cell Function and Diabetic Enteropathy

IGFBP3 and T1D: Systemic Factors in Colonic Stem Cell Function and Diabetic Enteropathy

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Author(s)
Cheng, Chia-Wei
•
Yilmaz, Omer
Alternative Title
IGFBP3 and T1D: Systemic Factors in Colonic Stem Cell Function and Diabetic Enteropathy
Date Issued
October 2015
Journal
Cell Stem Cell
Publisher
Elsevier
Citation
Cheng, Chia-Wei, and Yilmaz, Ömer H. “IGFBP3 and T1D: Systemic Factors in Colonic Stem Cell Function and Diabetic Enteropathy.” Cell Stem Cell 17, 4 (October 2015): 379–380 © 2015 Elsevier Inc
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Original manuscript
Abstract
Patients with type 1 diabetes (T1D) often experience gastrointestinal enteropathy (DE) of unclear etiology. Now in Cell Stem Cell, D’Addio et al. (2015) utilize organoid culture models to study the roles of stem cells in DE and show that circulating IGF/IGFBP3 controls colonic stem cell function during homeostasis and in T1D patients.
MIT Department
Massachusetts Institute of Technology. Department of Biology
Koch Institute for Integrative Cancer Research at MIT
Terms of Use
Creative Commons Attribution-NonCommercial-NoDerivs License
http://creativecommons.org/licenses/by-nc-nd/4.0/
Persistent DSpace Link
http://hdl.handle.net/1721.1/112089
DOI of Published Version
https://doi.org/10.1016/j.stem.2015.09.008
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