IGFBP3 and T1D: Systemic Factors in Colonic Stem Cell Function and Diabetic Enteropathy
Name
Yilmaz_Dysregulated.pdf
Size
1.2 MB
Format
Adobe PDF
Checksum (MD5)
5a7c821950b642a7a27907336bf5e39c
Author(s) •
Cheng, Chia-Wei
Yilmaz, Omer
Alternative Title
IGFBP3 and T1D: Systemic Factors in Colonic Stem Cell Function and Diabetic Enteropathy
Date Issued
October 2015
Journal
Cell Stem Cell
Publisher
Elsevier
Citation
Cheng, Chia-Wei, and Yilmaz, Ömer H. “IGFBP3 and T1D: Systemic Factors in Colonic Stem Cell Function and Diabetic Enteropathy.” Cell Stem Cell 17, 4 (October 2015): 379–380 © 2015 Elsevier Inc
Version
Original manuscript
Abstract
Patients with type 1 diabetes (T1D) often experience gastrointestinal enteropathy (DE) of unclear etiology. Now in Cell Stem Cell, D’Addio et al. (2015) utilize organoid culture models to study the roles of stem cells in DE and show that circulating IGF/IGFBP3 controls colonic stem cell function during homeostasis and in T1D patients.
MIT Department
Massachusetts Institute of Technology. Department of Biology
Koch Institute for Integrative Cancer Research at MIT
Terms of Use
Creative Commons Attribution-NonCommercial-NoDerivs License
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1016/j.stem.2015.09.008