Emerging Trends in Micro- and Nanoscale Technologies in Medicine: From Basic Discoveries to Translation
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acsnano.7b01493.pdf
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Author(s) • • • • • • • • •
Aizenberg, Joanna
Analoui, Mostafa
Andrews, Anne M.
Mooney, David J.
Oklu, Rahmi
Peer, Dan
Stolzoff, Michelle
Webster, Thomas J.
Weiss, Paul S.
Alvarez, Mario Moises
Date Issued
June 2017
Journal
ACS Nano
Publisher
American Chemical Society (ACS)
Citation
Alvarez, Mario M. et al. “Emerging Trends in Micro- and Nanoscale Technologies in Medicine: From Basic Discoveries to Translation.” ACS Nano 11, 6 (May 2017): 5195–5214 © 2017 American Chemical Society
Version
Final published version
Abstract
We discuss the state of the art and innovative micro- and nanoscale technologies that are finding niches and opening up new opportunities in medicine, particularly in diagnostic and therapeutic applications. We take the design of point-of-care applications and the capture of circulating tumor cells as illustrative examples of the integration of micro- and nanotechnologies into solutions of diagnostic challenges. We describe several novel nanotechnologies that enable imaging cellular structures and molecular events. In therapeutics, we describe the utilization of micro- and nanotechnologies in applications including drug delivery, tissue engineering, and pharmaceutical development/testing. In addition, we discuss relevant challenges that micro- and nanotechnologies face in achieving cost-effective and widespread clinical implementation as well as forecasted applications of micro- and nanotechnologies in medicine.
MIT Department
Harvard University--MIT Division of Health Sciences and Technology
Massachusetts Institute of Technology. Department of Biological Engineering
Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
Massachusetts Institute of Technology. Department of Chemical Engineering
Massachusetts Institute of Technology. Department of Mechanical Engineering
Massachusetts Institute of Technology. Media Laboratory
Massachusetts Institute of Technology. Microsystems Technology Laboratories
McGovern Institute for Brain Research at MIT
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Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
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DOI of Published Version
https://doi.org/10.1021/ACSNANO.7B01493