Biomarkers and diagnostic tools for detection of Helicobacter pylori
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253_2016_Article_7495.pdf
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Author(s)
Khalilpour, Akbar
Kazemzadeh-Narbat, Mehdi
Tamayol, Ali
Oklu, Rahmi
Khademhosseini, Ali
Date Issued
April 2016
Journal
Applied Microbiology and Biotechnology
Publisher
Springer Berlin Heidelberg
Citation
Khalilpour, Akbar, Mehdi Kazemzadeh-Narbat, Ali Tamayol, Rahmi Oklu, and Ali Khademhosseini. “Biomarkers and Diagnostic Tools for Detection of Helicobacter Pylori.” Applied Microbiology and Biotechnology 100, no. 11 (April 15, 2016): 4723-4734.
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Author's final manuscript
Abstract
Helicobacter pylori is responsible for worldwide chronic bacterial infection in humans affecting approximately half of the world’s population. H. pylori is associated with significant morbidity and mortality including gastric cancer. The infection has both direct and indirect impacts on economic and overall well-being of patients; hence, there is a great need for diagnostic markers that could be used in the development of diagnostic kits. Here, we briefly review general aspects of H. pylori infection and the diagnostic biomarkers used in laboratory tests today with a focus on the potential role of microfluidic systems in future immunodiagnosis platforms.
MIT Department
Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Harvard University--MIT Division of Health Sciences and Technology
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Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
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DOI of Published Version
https://doi.org/10.1007/s00253-016-7495-7
