Cu-Catalyzed Arylation of Phenols: Synthesis of Sterically Hindered and Heteroaryl Diaryl Ethers
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Buchwald_Cu-Catalyzed.pdf
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Author(s)
Maiti, Debabrata
Buchwald, Stephen Leffler
Date Issued
February 2010
Journal
Journal of Organic Chemistry
Publisher
American Chemical Society
Citation
Maiti, Debabrata, and Stephen L. Buchwald. “Cu-Catalyzed Arylation of Phenols: Synthesis of Sterically Hindered and Heteroaryl Diaryl Ethers.” The Journal of Organic Chemistry 75.5 (2010): 1791–1794. Web.
Version
Author's final manuscript
Abstract
Cu-catalyzed O-arylation of phenols with aryl iodides and bromides can be performed under mild condition in DMSO/K3PO4 with use of picolinic acid as the ligand for copper. This method tolerates a variety of functional groups and is effective in the synthesis of hindered diaryl ethers and heteroaryl ethers.
MIT Department
Massachusetts Institute of Technology. Department of Chemistry
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Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
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DOI of Published Version
https://doi.org/10.1021/jo9026935
