Iron(II)-Catalyzed Trifluoromethylation of Potassium Vinyltrifluoroborates
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Buchwald_Iron (II).pdf
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Author(s)
Parsons, Andrew T.
Senecal, Todd D.
Buchwald, Stephen Leffler
Date Issued
February 2012
Journal
Angewandte Chemie International Edition
Publisher
Wiley Blackwell
Citation
Parsons, Andrew T., Todd D. Senecal, and Stephen L. Buchwald. “Iron(II)-Catalyzed Trifluoromethylation of Potassium Vinyltrifluoroborates.” Angewandte Chemie International Edition 51, no. 12 (March 19, 2012): 2947-2950.
Version
Author's final manuscript
Abstract
Exchanging BF[subscript 3] by CF[subscript 3]: The title reaction proceeds under exceedingly mild reaction conditions and provides 2-arylvinyl- and 2-heteroarylvinyl-substituted substrates with E/Z selectivities of more than 95:5. Experimental observations suggest that the reaction does not proceed through a transmetalation of the RBF[subscript 3]K species to the iron catalyst.
MIT Department
Massachusetts Institute of Technology. Department of Chemistry
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Creative Commons Attribution-Noncommercial-Share Alike 3.0
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DOI of Published Version
https://doi.org/10.1002/anie.201108267
