Editorial: Progress in understanding the immunogenetic basis of disease susceptibility and outcomes
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fgene-13-1007825.pdf
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485.12 KB
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Adobe PDF
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Author(s) • •
Bharani, Tina
Agarwal, Divyansh
Roach, Jared
Date Issued
August 25, 2022
Journal
Frontiers in Genetics
Publisher
Frontiers Media SA
Citation
Bharani T and Agarwal D (2022) Editorial: Progress in understanding the immunogenetic basis of disease susceptibility and outcomes. Front. Genet. 13:1007825.
Version
Final published version
Abstract
Advances in sequencing technologies over the last 2 decades have dramatically increased our understanding of the molecular and genetic basis of immune responses, which in turn has led to a better understanding of the mechanisms underlying immune tolerance and surveillance. Similarly, better human leukocyte antigen (HLA) typing has helped explain how different genomic signatures might affect the development of autoimmune diseases, and opened new avenues of investigation in transplantation. The aim of our research topic was to collect articles that present the most cutting-edge, relevant, and impactful pieces on the role and study of immunogenetic polymorphisms affecting differential susceptibility to human diseases.
Subjects
Immunogenetics
HLA
haplotype
natural killer cells
preeclaimpsia
pregnancy
MIT Department
Massachusetts Institute of Technology. Department of Biology
Terms of Use
Creative Commons Attribution
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.3389/fgene.2022.1007825