Waking up dormant tumors
Name
Tse-2011-Waking up dormant tumors.pdf
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117.04 KB
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Adobe PDF
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Author(s) •
Tse, Joyce C.
Kalluri, Raghu
Date Issued
June 2011
Journal
Breast Cancer Research
Publisher
BioMed Central Ltd.
Citation
Tse, Joyce C, and Raghu Kalluri. “Waking up Dormant Tumors.” Breast Cancer Research 13.3 (2011): 310. © 2011 BioMed Central Ltd.
Version
Final published version
Abstract
As appreciation grows for the contribution of the tumor microenvironment to the progression of cancer, new evidence accumulates to support that the participation of stromal cells can extend beyond the local environment. Recently, Elkabets and colleagues demonstrated a systemic interaction between cancer cells and distant bone marrow cells to support the growth of otherwise indolent tumor cells at a secondary site, raising thought-provoking questions regarding the involvement of stromal cells in maintaining metastatic dormancy.
MIT Department
Harvard University--MIT Division of Health Sciences and Technology
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Creative Commons Attribution
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DOI of Published Version
https://doi.org/10.1186/bcr2872