Revolutionizing standard operating procedures in biomanufacturing
Name
857789932-MIT.pdf
Description
Full printable version
Size
8.44 MB
Format
Adobe PDF
Checksum (MD5)
60a834a5cb0a14034a890384b2d44211
Author(s)
Nag, Aditya
Advisor(s)
Thomas Kochan and Anthony Sinskey.
Date Issued
2013
Publisher
Massachusetts Institute of Technology
Abstract
In its quest to become a High Reliability Performance (HRP) organization, Amgen manufacturing operations desires to further improve its adherence to, and effectiveness of, its standard operating procedures (SOPs). SOPs are expected to provide clear guidance to operators to enable them to perform their job safely and effectively. This thesis aims to take a step back and answer the question "What is the best way to provide information and instruction to floor operators in order for them to perform their job in the best way possible?" Our hypothesis is that SOPs with content and style customized to the needs of the user will enhance performance along key operational metrics. This thesis includes an analysis of the current challenges of Amgen's existing SOPs including comparison to external benchmarks and academic research. Subsequently, we provide a recommendation on future SOP content, style and supporting infrastructure informed by our research. The analysis concludes with the results of a pilot project designed to evaluate our hypothesis. The analysis indicates that while our initial findings are encouraging, further research is required to conclusively determine the validity of our hypothesis.
Description
Thesis (M.B.A.)--Massachusetts Institute of Technology, Sloan School of Management; and, (S.M.)--Massachusetts Institute of Technology, Engineering Systems Division; in conjunction with the Leaders for Global Operations Program at MIT, 2013.
Cataloged from PDF version of thesis.
Includes bibliographical references (p. 88).
Subjects
Sloan School of Management.
Engineering Systems Division.
Leaders for Global Operations Program.
MIT Department
Leaders for Global Operations Program at MIT
Massachusetts Institute of Technology. Engineering Systems Division
Sloan School of Management
Terms of Use
M.I.T. theses are protected by
copyright. They may be viewed from this source for any purpose, but
reproduction or distribution in any format is prohibited without written
permission. See provided URL for inquiries about permission.
copyright. They may be viewed from this source for any purpose, but
reproduction or distribution in any format is prohibited without written
permission. See provided URL for inquiries about permission.
Persistent DSpace Link
