Cell-Trappable Fluorescent Probes for Nitric Oxide Visualization in Living Cells
Name
Pluth et al Org Lett.pdf
Size
4.64 MB
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Adobe PDF
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e10542778ad9f5ffac74addeff5e40a0
Author(s)
Pluth, Michael D.
McQuade, Lindsey E.
Lippard, Stephen J.
Date Issued
March 2010
Journal
Organic Letters
Publisher
American Chemical Society
Citation
Pluth, Michael D., Lindsey E. McQuade, and Stephen J. Lippard. “Cell-Trappable Fluorescent Probes for Nitric Oxide Visualization in Living Cells.” Organic Letters 12.10 (2010) : 2318-2321.
Version
Author's final manuscript
Abstract
Two new cell-trappable fluorescent probes for nitric oxide (NO) are reported based on either incorporation of hydrolyzable esters or conjugation to aminodextran polymers. Both probes are highly selective for NO over other reactive oxygen and nitrogen species (RONS). The efficacy of these probes for the fluorescence imaging of nitric oxide produced endogenously in Raw 264.7 cells is demonstrated.
MIT Department
Massachusetts Institute of Technology. Department of Chemistry
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Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.
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DOI of Published Version
https://doi.org/10.1021/ol1006289
