Vascular Response to Experimental Stent Malapposition and Under-Expansion
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Author(s) • • • • • • • • •
Bailey, Lynn
Markham, Peter
Costa, Marco
Ware, James
O'Brien, Caroline C.
Lopes Jr, Augusto Celso de Araujo
Kolandaivelu, Kumaran
Kunio, Mie
Brown, Jonathan
Kolachalama, Vijaya Bhasker
Date Issued
January 2016
Journal
Annals of Biomedical Engineering
Publisher
Springer US
Citation
O’Brien, Caroline C., Augusto C. Lopes, Kumaran Kolandaivelu, Mie Kunio, Jonathan Brown, Vijaya B. Kolachalama, Claire Conway, et al. “Vascular Response to Experimental Stent Malapposition and Under-Expansion.” Ann Biomed Eng 44, no. 7 (January 5, 2016): 2251–2260.
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Author's final manuscript
Abstract
Up to 80% of all endovascular stents have malapposed struts, and while some impose catastrophic events others are inconsequential. Thirteen stents were implanted in coronary arteries of seven healthy Yorkshire pigs, using specially-designed cuffed balloons inducing controlled stent malapposition and under-expansion. Optical coherence tomography (OCT) imaging confirmed that 25% of struts were malapposed (strut-wall distance
MIT Department
Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Harvard University--MIT Division of Health Sciences and Technology
Massachusetts Institute of Technology. School of Engineering
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DOI of Published Version
https://doi.org/10.1007/s10439-015-1518-x