Pathology of Endovascular Stents
Name
Pathology of endovascular.pdf
Size
904.25 KB
Format
Adobe PDF
Checksum (MD5)
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Author(s)
Keating, John H.
Nakamura, Kenta
Edelman, Elazer R
Date Issued
May 2016
Journal
Interventional Cardiology Clinics
Publisher
Elsevier BV
Citation
Nakamura, Kenta et al. “Pathology of Endovascular Stents.” Interventional Cardiology Clinics 5, 3 (July 2016): 391–403 © 2016 Elsevier Inc
Version
Author's final manuscript
Abstract
Contemporary endovascular stents are the product of an iterative design and development process that leverages evolving concepts in vascular biology and engineering. This article reviews how insights into vascular pathophysiology, materials science, and design mechanics drive stent design and explain modes of stent failure. Current knowledge of pathologic processes is providing a more complete picture of the factors mediating stent failure. Further evolution of endovascular stents includes bioresorbable platforms tailored to treat plaques acutely and to then disappear after lesion pacification. Ongoing refinement of stent technology will continue to require insights from pathology to understand adverse events, refine clinical protocols, and drive innovation. Keywords: Coronary artery disease; Pathology; Bare metal stent; Drug-eluting stent; In-stent restenosis; In-stent thrombosis; Atherosclerosis; Neoatherosclerosis
MIT Department
Institute for Medical Engineering and Science
Terms of Use
Creative Commons Attribution-NonCommercial-NoDerivs License
Persistent DSpace Link
DOI of Published Version
https://doi.org/10.1016/J.ICCL.2016.02.006
